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The neonatal anti-viral response fails to control measles virus spread in neurons despite interferon-gamma expression and a Th1-like cytokine profile

Neonates are highly susceptible to viral infections in the periphery, potentially due to deviant cytokine responses. Here, we investigated the role of interferon-gamma (IFNγ), a key anti-viral in the neonatal brain. We found that (i) IFNγ, which is critical for viral control and survival in adults,...

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Dades bibliogràfiques
Publicat a:J Neuroimmunol
Autors principals: Ganesan, Priya, Chandwani, Manisha N., Creisher, Patrick S., Bohn, Larissa, O'Donnell, Lauren A.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier B.V. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003673/
https://ncbi.nlm.nih.gov/pubmed/29366594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2017.12.018
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