Polypentagonal ice-like water networks emerge solely in an activity-improved variant of ice-binding protein

Polypentagonal water networks were recently observed in a protein capable of binding to ice crystals, or ice-binding protein (IBP). To examine such water networks and clarify their role in ice-binding, we determined X-ray crystal structures of a 65-residue defective isoform of a Zoarcidae-derived IB...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Mahatabuddin, Sheikh, Fukami, Daichi, Arai, Tatsuya, Nishimiya, Yoshiyuki, Shimizu, Rumi, Shibazaki, Chie, Kondo, Hidemasa, Adachi, Motoyasu, Tsuda, Sakae
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003529/
https://ncbi.nlm.nih.gov/pubmed/29735675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1800635115
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