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Staphylococcus aureus clumping factor A is a force-sensitive molecular switch that activates bacterial adhesion

Clumping factor A (ClfA), a cell-wall–anchored protein from Staphylococcus aureus, is a virulence factor in various infections and facilitates the colonization of protein-coated biomaterials. ClfA promotes bacterial adhesion to the blood plasma protein fibrinogen (Fg) via molecular forces that have...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Herman-Bausier, Philippe, Labate, Cristina, Towell, Aisling M., Derclaye, Sylvie, Geoghegan, Joan A., Dufrêne, Yves F.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003445/
https://ncbi.nlm.nih.gov/pubmed/29735708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718104115
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