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Cdk1-dependent phosphoinhibition of a formin-F-BAR interaction opposes cytokinetic contractile ring formation

In Schizosaccharomyces pombe, cytokinesis requires the assembly and constriction of an actomyosin-based contractile ring (CR). A single essential formin, Cdc12, localizes to the cell middle upon mitotic onset and nucleates the F-actin of the CR. Cdc12 medial recruitment is mediated in part by its di...

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Bibliografiske detaljer
Udgivet i:Mol Biol Cell
Main Authors: Willet, Alaina H., Bohnert, K. Adam, Gould, Kathleen L.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003227/
https://ncbi.nlm.nih.gov/pubmed/29343550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-11-0646
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