Transcriptional Repression of p53 by PAX3 Contributes to Gliomagenesis and Differentiation of Glioma Stem Cells

Although there are available therapies as surgery, chemotherapy and radiation, glioblastoma (GBM) still has been considered as the most common and overwhelming primary tumor of brain. In GBM, the brain glioma stem cells (BGSCs) were identified and played a crucial role in resistance of GBM to conven...

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Vydáno v:Front Mol Neurosci
Hlavní autoři: Zhu, Hui, Wang, Hongkui, Huang, Qingfeng, Liu, Qianqian, Guo, Yibing, Lu, Jingjing, Li, Xiaohong, Xue, Chengbin, Han, Qianqian
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003214/
https://ncbi.nlm.nih.gov/pubmed/29937714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00187
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