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Alternative-splicing defects in cancer: splicing regulators and their downstream targets, guiding the way to novel cancer therapeutics
Defects in alternative splicing are frequently found in human tumors and result either from mutations in splicing-regulatory elements of specific cancer genes or from changes in the regulatory splicing machinery. RNA splicing regulators have emerged as a new class of oncoproteins and tumor suppresso...
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| Veröffentlicht in: | Wiley Interdiscip Rev RNA |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6002934/ https://ncbi.nlm.nih.gov/pubmed/29693319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1476 |
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