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Epigenetic regulation of the nitric oxide pathway, 17-alpha hydroxyprogesterone caproate, and recurrent preterm birth

OBJECTIVE: We sought to evaluate nitric oxide pathway placental gene expression and the epigenome (CpG methylation) among women receiving 17-alpha hydroxyprogesterone caproate (17-OHPC) with and without recurrent preterm birth (PTB). STUDY DESIGN: Case-control study. We prospectively recruited women...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Perinatol
Hauptverfasser: MANUCK, Tracy A., SMEESTER, Lisa, MARTIN, Elizabeth M., TOMLINSON, Martha S., SMITH, Christina, VARNER, Michael W., FRY, Rebecca C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002888/
https://ncbi.nlm.nih.gov/pubmed/29241278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0037-1613682
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