Use of Haploid Model of Candida albicans to Uncover Mechanism of Action of a Novel Antifungal Agent

Antifungal agents for the treatment of Candida albicans infections are limited. We recently discovered a novel antifungal small molecule, SM21, with promising in vivo activity. Herein, we employed the newly developed C. albicans haploid toolbox to uncover the mechanism of action of SM21. Comprehensi...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Truong, Thuyen, Suriyanarayanan, Tanujaa, Zeng, Guisheng, Le, Thuc D., Liu, Lin, Li, Jiuyong, Tong, Cao, Wang, Yue, Seneviratne, Chaminda J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002804/
https://ncbi.nlm.nih.gov/pubmed/29938200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2018.00164
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