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Interferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20

Bunyaviruses pose a significant threat to human health, prosperity, and food security. In response to viral infections, interferons (IFNs) upregulate the expression of hundreds of interferon-stimulated genes (ISGs), whose cumulative action can potently inhibit the replication of bunyaviruses. We use...

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Publicado en:J Virol
Autores principales: Feng, Junjie, Wickenhagen, Arthur, Turnbull, Matthew L., Rezelj, Veronica V., Kreher, Felix, Tilston-Lunel, Natasha L., Slack, Gillian S., Brennan, Benjamin, Koudriakova, Elina, Shaw, Andrew E., Rihn, Suzannah J., Rice, Charles M., Bieniasz, Paul D., Elliott, Richard M., Shi, Xiaohong, Wilson, Sam J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002717/
https://ncbi.nlm.nih.gov/pubmed/29695422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02140-17
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