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Anti-phage islands force their target phage to directly mediate island excision and spread

Vibrio cholerae, the causative agent of the diarrheal disease cholera, is antagonized by the lytic phage ICP1 in the aquatic environment and in human hosts. Mobile genetic elements called PLEs (phage-inducible chromosomal island-like elements) protect V. cholerae from ICP1 infection and initiate the...

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Bibliographic Details
Published in:Nat Commun
Main Authors: McKitterick, Amelia C., Seed, Kimberley D.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002521/
https://ncbi.nlm.nih.gov/pubmed/29904071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04786-5
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