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Building predictive in vitro pulmonary toxicity assays using high-throughput imaging and artificial intelligence

Human lungs are susceptible to the toxicity induced by soluble xenobiotics. However, the direct cellular effects of many pulmonotoxic chemicals are not always clear, and thus, a general in vitro assay for testing pulmonotoxicity applicable to a wide variety of chemicals is not currently available. H...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Arch Toxicol
Hauptverfasser: Lee, Jia-Ying Joey, Miller, James Alastair, Basu, Sreetama, Kee, Ting-Zhen Vanessa, Loo, Lit-Hsin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002469/
https://ncbi.nlm.nih.gov/pubmed/29705884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-018-2213-0
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