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Decreased monocyte shedding of the migration inhibitor soluble CD18 in alcoholic hepatitis

OBJECTIVES: During alcoholic hepatitis (AH) monocytes traverse the vascular boundaries and massively invade the liver. In principle, tissue extravasation can be limited through shedding of CD18 integrins from leukocytes, including monocytes. The soluble (s) product sCD18 conceals adhesion receptors...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clin Transl Gastroenterol
Hauptverfasser: Støy, Sidsel, Sandahl, Thomas Damgaard, Hansen, Anne Louise, Deleuran, Bent, Vorup-Jensen, Thomas, Vilstrup, Hendrik, Kragstrup, Tue Wenzel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group US 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002386/
https://ncbi.nlm.nih.gov/pubmed/29904132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41424-018-0022-7
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