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Cholera toxin enhances interleukin‐17A production in both CD4(+) and CD8(+) cells via a cAMP/protein kinase A‐mediated interleukin‐17A promoter activation

Cholera toxin (CT) is a bacterial component that increases intracellular cAMP levels in host cells and suppresses T‐cell activation. Recently, CT was reported to induce T helper type 17‐skewing dendritic cells and activate interleukin‐17A (IL‐17A) production in CD4(+) T cells through a cAMP‐dependen...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Tsai, Hsing‐Chuan, Velichko, Sharlene, Lee, Shanshan, Wu, Reen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002222/
https://ncbi.nlm.nih.gov/pubmed/29377102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12900
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