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Hypoxia‐inducible transcription factors, HIF1A and HIF2A, increase in aging mucosal tissues

Hypoxia (i.e. oxygen deprivation) activates the hypoxia‐signalling pathway, primarily via hypoxia‐inducible transcription factors (HIF) for numerous target genes, which mediate angiogenesis, metabolism and coagulation, among other processes to try to replenish tissues with blood and oxygen. Hypoxia...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Ebersole, Jeffrey L., Novak, Michael John, Orraca, Luis, Martinez‐Gonzalez, Janis, Kirakodu, Sreenatha, Chen, Kuey C., Stromberg, Arnold, Gonzalez, Octavio A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002220/
https://ncbi.nlm.nih.gov/pubmed/29338076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12894
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