Phosphorylation of Beta-3 adrenergic receptor at serine 247 by ERK MAP kinase drives lipolysis in obese adipocytes

OBJECTIVE: The inappropriate release of free fatty acids from obese adipose tissue stores has detrimental effects on metabolism, but key molecular mechanisms controlling FFA release from adipocytes remain undefined. Although obesity promotes systemic inflammation, we find activation of the inflammat...

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Gepubliceerd in:Mol Metab
Hoofdauteurs: Hong, Shangyu, Song, Wei, Zushin, Peter-James H., Liu, Bingyang, Jedrychowski, Mark P., Mina, Amir I., Deng, Zhaoming, Cabarkapa, Dimitrije, Hall, Jessica A., Palmer, Colin J., Aliakbarian, Hassan, Szpyt, John, Gygi, Steven P., Tavakkoli, Ali, Lynch, Lydia, Perrimon, Norbert, Banks, Alexander S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2018
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001906/
https://ncbi.nlm.nih.gov/pubmed/29661693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.03.012
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