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How well do force fields capture the strength of salt bridges in proteins?

Salt bridges form between pairs of ionisable residues in close proximity and are important interactions in proteins. While salt bridges are known to be important both for protein stability, recognition and regulation, we still do not have fully accurate predictive models to assess the energetic cont...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Ahmed, Mustapha Carab, Papaleo, Elena, Lindorff-Larsen, Kresten
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001725/
https://ncbi.nlm.nih.gov/pubmed/29910983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.4967
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