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Chronic Alcohol Consumption Inhibits Autophagy and Promotes Apoptosis in the Liver

Background: Chronic alcohol consumption is a major cause of liver injury. However, the molecular mechanisms by which alcohol impairs hepatocellular function and induces cell death remain unclear. Macroautophagy (hereafter called 'autophagy') is a degradation pathway involved in the surviva...

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Detalhes bibliográficos
Publicado no:Int J Med Sci
Main Authors: Menk, Mario, Graw, Jan Adriaan, Poyraz, Deniz, Möbius, Nadine, Spies, Claudia D., von Haefen, Clarissa
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001414/
https://ncbi.nlm.nih.gov/pubmed/29910672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.25393
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