Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity

OBJECTIVE: Given that cellular O-GlcNAcylation levels are thought to be real-time measures of cellular nutrient status and dysregulated O-GlcNAc signaling is associated with insulin resistance, we evaluated the role of O-GlcNAc transferase (OGT), the enzyme that mediates O-GlcNAcylation, in skeletal...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Shi, Hao, Munk, Alexander, Nielsen, Thomas S., Daughtry, Morgan R., Larsson, Louise, Li, Shize, Høyer, Kasper F., Geisler, Hannah W., Sulek, Karolina, Kjøbsted, Rasmus, Fisher, Taylor, Andersen, Marianne M., Shen, Zhengxing, Hansen, Ulrik K., England, Eric M., Cheng, Zhiyong, Højlund, Kurt, Wojtaszewski, Jørgen F.P., Yang, Xiaoyong, Hulver, Matthew W., Helm, Richard F., Treebak, Jonas T., Gerrard, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001359/
https://ncbi.nlm.nih.gov/pubmed/29525407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.02.010
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