Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity

OBJECTIVE: Given that cellular O-GlcNAcylation levels are thought to be real-time measures of cellular nutrient status and dysregulated O-GlcNAc signaling is associated with insulin resistance, we evaluated the role of O-GlcNAc transferase (OGT), the enzyme that mediates O-GlcNAcylation, in skeletal...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Mol Metab
Main Authors: Shi, Hao, Munk, Alexander, Nielsen, Thomas S., Daughtry, Morgan R., Larsson, Louise, Li, Shize, Høyer, Kasper F., Geisler, Hannah W., Sulek, Karolina, Kjøbsted, Rasmus, Fisher, Taylor, Andersen, Marianne M., Shen, Zhengxing, Hansen, Ulrik K., England, Eric M., Cheng, Zhiyong, Højlund, Kurt, Wojtaszewski, Jørgen F.P., Yang, Xiaoyong, Hulver, Matthew W., Helm, Richard F., Treebak, Jonas T., Gerrard, David E.
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier 2018
נושאים:
Original Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001359/
https://ncbi.nlm.nih.gov/pubmed/29525407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.02.010
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