RGS14 Restricts Plasticity in Hippocampal CA2 by Limiting Postsynaptic Calcium Signaling

Pyramidal neurons in hippocampal area CA2 are distinct from neighboring CA1 in that they resist synaptic long-term potentiation (LTP) at CA3 Schaffer collateral synapses. Regulator of G protein signaling 14 (RGS14) is a complex scaffolding protein enriched in CA2 dendritic spines that naturally bloc...

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Publicat a:eNeuro
Autors principals: Evans, Paul R., Parra-Bueno, Paula, Smirnov, Michael S., Lustberg, Daniel J., Dudek, Serena M., Hepler, John R., Yasuda, Ryohei
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2018
Matèries:
New Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001268/
https://ncbi.nlm.nih.gov/pubmed/29911178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0353-17.2018
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