A cost effective RFLP method to genotype Solute carrier organic anion 1B1 (SLCO1B1) c.1929A>C (p.Leu643Phe, rs34671512); a variant with potential effect on rosuvastatin pharmacokinetics

OBJECTIVE: This study describes a restriction fragment polymorphism protocol for rapidly screening the polymorphism SLCO1B1 c.1929A>C in genomic DNA samples. The polymorphism SLCO1B1 c.1929A>C has been associated with increased activity resulting in increased hepatic uptake of drugs. Currently...

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Publicat a:BMC Res Notes
Autors principals: Soko, Nyarai D., Masimirembwa, Collen, Dandara, Collet
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research Note
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6000981/
https://ncbi.nlm.nih.gov/pubmed/29898760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-018-3469-4
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