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LRRK 2 gene mutations in the pathophysiology of the ROCO domain and therapeutic targets for Parkinson’s disease: a review

Parkinson’s disease (PD) is the most common movement disorder and manifests as resting tremor, rigidity, bradykinesia, and postural instability. Pathologically, PD is characterized by selective loss of dopaminergic neurons in the substantia nigra and the formation of intracellular inclusions contain...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biomed Sci
Main Authors: Chen, Meng-Ling, Wu, Ruey-Meei
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6000924/
https://ncbi.nlm.nih.gov/pubmed/29903014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-018-0454-0
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