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非小细胞肺癌的BRAF基因突变及其临床意义

BRAF mutations have been found to be a driver mutation and maybe a therapy target in patients with non-small cell lung cancer. This article reviews the current understanding of BRAF gene, its structure, expression, the signal pathway, as well as its relationship with cancer especially the targeted t...

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Bibliographic Details
Published in:Zhongguo Fei Ai Za Zhi
Format: Artigo
Language:Inglês
Published: 中国肺癌杂志编辑部 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999868/
https://ncbi.nlm.nih.gov/pubmed/22429583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3779/j.issn.1009-3419.2012.03.09
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