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Description of A New Oncogenic Mechanism for Atypical Teratoid Rhabdoid Tumors in Patients with Ring Chromosome 22

Atypical teratoid rhabdoid tumors of the central nervous system are rare, highly malignant, embryonal tumors most often occurring in children under age 3 years. Most are due to a somatic change in tumor suppressor gene SMARCB1 followed by a second-hit, typically loss of heterozygosity, best detected...

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Detalhes bibliográficos
Publicado no:Am J Med Genet A
Main Authors: Byers, Heather M., Adam, Margaret P., LaCroix, Amy, Leary, Sarah E.S., Cole, Bonnie, Dobyns, William B., Mefford, Heather C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999866/
https://ncbi.nlm.nih.gov/pubmed/27734605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.37993
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