Hedgehog signalling in the tumourigenesis and metastasis of osteosarcoma, and its potential value in the clinical therapy of osteosarcoma

The Hedgehog (Hh) signalling pathway is involved in cell differentiation, growth and tissue polarity. This pathway is also involved in the progression and invasion of various human cancers. Osteosarcoma, a subtype of bone cancer, is commonly seen in children and adolescents. Typically, pulmonary ost...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Yao, Zhihong, Han, Lei, Chen, Yongbin, He, Fei, Sun, Bin, kamar, Santosh, Zhang, Ya, Yang, Yihao, Wang, Cao, Yang, Zuozhang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999604/
https://ncbi.nlm.nih.gov/pubmed/29899399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0647-1
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