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Biased agonism: the quest for the analgesic holy grail
Opioids alleviate pain, but adverse effects severely limit their usefulness. To solve this problem, biased ligands favoring 1 signaling pathway downstream of the μ-opioid receptor over another are being developed. In the target article, the authors synthesize compounds that preferentially activate G...
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| Publicado no: | Pain Rep |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wolters Kluwer
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5999417/ https://ncbi.nlm.nih.gov/pubmed/29922742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PR9.0000000000000650 |
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