A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas

Paclitaxel is a powerful chemotherapeutic drug, used for the treatment of many cancer types, including esophageal adenocarcinomas (EAC). Autophagy is a lysosome-dependent degradation process maintaining cellular homeostasis. Defective autophagy has been implicated in cancer biology and therapy resis...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Adams, Olivia, Janser, Félice A., Dislich, Bastian, Berezowska, Sabina, Humbert, Magali, Seiler, Christian A., Kroell, Dino, Slotta-Huspenina, Julia, Feith, Marcus, Ott, Katja, Tschan, Mario P., Langer, Rupert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999293/
https://ncbi.nlm.nih.gov/pubmed/29897944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197610
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