Targeted massively parallel sequencing characterises the mutation spectrum of PALB2 in breast and ovarian cancer cases from Poland and Ukraine

Loss-of-function germline mutations in the PALB2 gene are associated with an increase of breast cancer risk. The purpose of this study was to characterise the spectrum of PALB2 mutations in women affected with breast or ovarian cancer from South-West Poland and West Ukraine. We applied Hi-Plex, an a...

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Detalhes bibliográficos
Publicado no:Fam Cancer
Main Authors: Myszka, Aleksander, Nguyen-Dumont, Tu, Karpinski, Pawel, Sasiadek, Maria M., Akopyan, Hayane, Hammet, Fleur, Tsimiklis, Helen, Park, Daniel J., Pope, Bernard J., Slezak, Ryszard, Kitsera, Nataliya, Siekierzynska, Aleksandra, Southey, Melissa C.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999175/
https://ncbi.nlm.nih.gov/pubmed/29052111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-017-0050-6
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