The metalloprotease ADAM10 (a disintegrin and metalloprotease 10) undergoes rapid, postlysis autocatalytic degradation

The transmembrane protein, ADAM10 (a disintegrin and metalloprotease 10), has key physiologic functions—for example, during embryonic development and in the brain. During transit through the secretory pathway, immature ADAM10 (proADAM10) is converted into its proteolytically active, mature form (mAD...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Brummer, Tobias, Pigoni, Martina, Rossello, Armando, Wang, Huanhuan, Noy, Peter J., Tomlinson, Michael G., Blobel, Carl P., Lichtenthaler, Stefan F.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998973/
https://ncbi.nlm.nih.gov/pubmed/29430990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700823RR
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