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Understanding the tumor immune microenvironment (TIME) for effective therapy

The clinical successes in immunotherapy have been both astounding and at the same time unsatisfactory. Countless patients with varied tumor types have seen pronounced clinical response with immunotherapeutic intervention; however, many more patients have experienced minimal or no clinical benefit wh...

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Vydáno v:Nat Med
Hlavní autoři: Binnewies, Mikhail, Roberts, Edward W., Kersten, Kelly, Chan, Vincent, Fearon, Douglas F., Merad, Miriam, Coussens, Lisa M., Gabrilovich, Dmitry I., Ostrand-Rosenberg, Suzanne, Hedrick, Catherine C., Vonderheide, Robert H., Pittet, Mikael J., Jain, Rakesh K., Zou, Weiping, Howcroft, T. Kevin, Woodhouse, Elisa C., Weinberg, Robert A., Krummel, Matthew F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998822/
https://ncbi.nlm.nih.gov/pubmed/29686425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0014-x
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