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HDAC1 and HDAC2 Modulate TGF-β Signaling during Endothelial-to-Hematopoietic Transition

The first hematopoietic stem and progenitor cells are generated during development from hemogenic endothelium (HE) through trans-differentiation. The molecular mechanisms underlying this endothelial-to-hematopoietic transition (EHT) remain poorly understood. Here, we explored the role of the epigene...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Thambyrajah, Roshana, Fadlullah, Muhammad Z.H., Proffitt, Martin, Patel, Rahima, Cowley, Shaun M., Kouskoff, Valerie, Lacaud, Georges
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998800/
https://ncbi.nlm.nih.gov/pubmed/29641990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.03.011
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