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In silico prediction of potential chemical reactions mediated by human enzymes

BACKGROUND: Administered drugs are often converted into an ineffective or activated form by enzymes in our body. Conventional in silico prediction approaches focused on therapeutically important enzymes such as CYP450. However, there are more than thousands of different cellular enzymes that potenti...

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מידע ביבליוגרפי
הוצא לאור ב:BMC Bioinformatics
Main Authors: Yu, Myeong-Sang, Lee, Hyang-Mi, Park, Aaron, Park, Chungoo, Ceong, Hyithaek, Rhee, Ki-Hyeong, Na, Dokyun
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998764/
https://ncbi.nlm.nih.gov/pubmed/29897324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2194-2
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