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In utero electroporation induces cell death and alters embryonic microglia morphology and expression signatures in the developing hypothalamus

BACKGROUND: Since its inception in 2001, in utero electroporation (IUE) has been widely used by the neuroscience community. IUE is a technique developed to introduce plasmid DNA into embryonic mouse brains without permanently removing the embryos from the uterus. Given that IUE labels cells that lin...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Rosin, Jessica M., Kurrasch, Deborah M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998590/
https://ncbi.nlm.nih.gov/pubmed/29895301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1213-6
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