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AMPK-α1 or AMPK-α2 Deletion in Smooth Muscles Does Not Affect the Hypoxic Ventilatory Response or Systemic Arterial Blood Pressure Regulation During Hypoxia

The hypoxic ventilatory response (HVR) is markedly attenuated by AMPK-α1 deletion conditional on the expression of Cre-recombinase in tyrosine hydroxylase (TH) expressing cells, precipitating marked increases in apnea frequency and duration. It was concluded that ventilatory dysfunction caused by AM...

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Bibliografiske detaljer
Udgivet i:Front Physiol
Main Authors: MacMillan, Sandy, Evans, A. Mark
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997817/
https://ncbi.nlm.nih.gov/pubmed/29928235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00655
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