UNC-16/JIP3 and UNC-76/FEZ1 limit the density of mitochondria in C. elegans neurons by maintaining the balance of anterograde and retrograde mitochondrial transport

We investigate the role of axonal transport in regulating neuronal mitochondrial density. We show that the density of mitochondria in the touch receptor neuron (TRN) of adult Caenorhabditis elegans is constant. Mitochondrial density and transport are controlled both by the Kinesin heavy chain and th...

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Publicat a:Sci Rep
Autors principals: Sure, Guruprasada Reddy, Chatterjee, Anusheela, Mishra, Nikhil, Sabharwal, Vidur, Devireddy, Swathi, Awasthi, Anjali, Mohan, Swetha, Koushika, Sandhya P.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997755/
https://ncbi.nlm.nih.gov/pubmed/29895958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27211-9
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