UNC-16/JIP3 and UNC-76/FEZ1 limit the density of mitochondria in C. elegans neurons by maintaining the balance of anterograde and retrograde mitochondrial transport

We investigate the role of axonal transport in regulating neuronal mitochondrial density. We show that the density of mitochondria in the touch receptor neuron (TRN) of adult Caenorhabditis elegans is constant. Mitochondrial density and transport are controlled both by the Kinesin heavy chain and th...

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Vydáno v:Sci Rep
Hlavní autoři: Sure, Guruprasada Reddy, Chatterjee, Anusheela, Mishra, Nikhil, Sabharwal, Vidur, Devireddy, Swathi, Awasthi, Anjali, Mohan, Swetha, Koushika, Sandhya P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997755/
https://ncbi.nlm.nih.gov/pubmed/29895958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27211-9
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