UNC-16/JIP3 and UNC-76/FEZ1 limit the density of mitochondria in C. elegans neurons by maintaining the balance of anterograde and retrograde mitochondrial transport

We investigate the role of axonal transport in regulating neuronal mitochondrial density. We show that the density of mitochondria in the touch receptor neuron (TRN) of adult Caenorhabditis elegans is constant. Mitochondrial density and transport are controlled both by the Kinesin heavy chain and th...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Sure, Guruprasada Reddy, Chatterjee, Anusheela, Mishra, Nikhil, Sabharwal, Vidur, Devireddy, Swathi, Awasthi, Anjali, Mohan, Swetha, Koushika, Sandhya P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997755/
https://ncbi.nlm.nih.gov/pubmed/29895958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27211-9
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