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Human trophoblast stem cell self-renewal and differentiation: Role of decorin

The origin and regulation of stem cells sustaining trophoblast renewal in the human placenta remain unclear. Decorin, a leucine-rich proteoglycan restrains trophoblast proliferation, migration/invasiveness and endovascular differentiation, and local decorin overproduction is associated with preeclam...

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Foilsithe in:Sci Rep
Main Authors: Nandi, Pinki, Lim, Hyobin, Torres-Garcia, Eloy Jose, Lala, Peeyush K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997742/
https://ncbi.nlm.nih.gov/pubmed/29895842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27119-4
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