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Coping with- and leveraging uncertainty in the response of individual cells to therapy

Non-genetic heterogeneity fluctuates over diverse timescales, ranging from hours to months. In specific cases, such variability can profoundly impact the response of cell populations to therapy, in both antibiotic treatments in bacteria and chemotherapy in cancer. It is thus critical to understand t...

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Detalhes bibliográficos
Publicado no:Curr Opin Biotechnol
Main Authors: Reyes, José, Lahav, Galit
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997492/
https://ncbi.nlm.nih.gov/pubmed/29288931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.copbio.2017.12.007
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