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Cell-surface G-protein-coupled receptors for tumor-associated metabolites: A direct link to mitochondrial dysfunction in cancer

Mitochondria are the sites of pyruvate oxidation, citric acid cycle, oxidative phosphorylation, ketogenesis, and fatty acid oxidation. Attenuation of mitochondrial function is one of the most significant changes that occurs in tumor cells, directly linked to oncogenesis, angiogenesis, Warburg effect...

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Bibliografiske detaljer
Udgivet i:Biochim Biophys Acta
Main Authors: Ristic, Bojana, Bhutia, Yangzom D., Ganapathy, Vadivel
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997391/
https://ncbi.nlm.nih.gov/pubmed/28512002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2017.05.003
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