Investigating the interplay between substrate stiffness and ligand chemistry in directing mesenchymal stem cell differentiation within 3D macro-porous substrates

Dimensionality can have a profound impact on stiffness-mediated differentiation of mesenchymal stem cells (MSCs). However, while we have begun to understand cellular response when encapsulated within 3D substrates, the behavior of cells within macro-porous substrates is relatively underexplored. The...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Haugh, Matthew G., Vaughan, Ted J., Madl, Christopher M., Raftery, Rosanne M., McNamara, Laoise M., O’Brien, Fergal J., Heilshorn, Sarah C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997298/
https://ncbi.nlm.nih.gov/pubmed/29677521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2018.04.026
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