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Chloroquine-containing DMAEMA copolymers as efficient anti-miRNA delivery vectors with improved endosomal escape and anti-migratory activity in cancer cells

Chloroquine-containing 2-(dimethylamino)ethyl methacrylate (DMAEMA) copolymers (PDCs) were synthesized by reversible addition-fragmentation chain-transfer (RAFT) polymerization. Systematic evaluation was performed to test the hypothesis that presence of chloroquine (CQ) in the PDC structure will imp...

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Detalhes bibliográficos
Publicado no:Macromol Biosci
Main Authors: Xie, Ying, Yu, Fei, Tang, Weimin, Alade, Bolutito, Peng, Zheng-Hong, Wang, Yazhe, Li, Jing, Oupický, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997184/
https://ncbi.nlm.nih.gov/pubmed/28776937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mabi.201700194
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