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The Na(+)(K(+))/H(+) exchanger Nhx1 controls multivesicular body–vacuolar lysosome fusion

Loss-of-function mutations in human endosomal Na(+)(K(+))/H(+) exchangers (NHEs) NHE6 and NHE9 are implicated in neurological disorders including Christianson syndrome, autism, and attention deficit and hyperactivity disorder. These mutations disrupt retention of surface receptors within neurons and...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Karim, Mahmoud Abdul, Brett, Christopher Leonard
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996954/
https://ncbi.nlm.nih.gov/pubmed/29212874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-08-0496
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