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Primary Human Microglia Are Phagocytically Active and Respond to Borrelia burgdorferi With Upregulation of Chemokines and Cytokines

The Lyme disease causing bacterium Borrelia burgdorferi has an affinity for the central nervous system (CNS) and has been isolated from human cerebral spinal fluid by 18 days following Ixodes scapularis tick bite. Signaling from resident immune cells of the CNS could enhance CNS penetration by B. bu...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Greenmyer, Jacob R., Gaultney, Robert A., Brissette, Catherine A., Watt, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996889/
https://ncbi.nlm.nih.gov/pubmed/29922241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00811
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