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Modeling Keratoconus Using Induced Pluripotent Stem Cells

PURPOSE: To model keratoconus (KC) using induced pluripotent stem cells (iPSC) generated from fibroblasts of both KC and normal human corneal stroma by a viral method. METHODS: Both normal and KC corneal fibroblasts from four human donors were reprogramed directly by delivering reprogramming factors...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Joseph, Roy, Srivastava, Om P., Pfister, Roswell R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996875/
https://ncbi.nlm.nih.gov/pubmed/27403997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-19105
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