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Promyelocytic Leukemia Restricts Enterovirus 71 Replication by Inhibiting Autophagy

The promyelocytic leukemia (PML) protein, also known as TRIM19, functions as a major organizer of PML nuclear bodies (NBs) in most mammalian cells and plays important roles in antiviral activities against both DNA and RNA viruses. In this study, we found that the downregulation of PML rendered HeLa...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Chen, Deyan, Feng, Chunhong, Tian, Xiaoyan, Zheng, Nan, Wu, Zhiwei
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996053/
https://ncbi.nlm.nih.gov/pubmed/29922292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01268
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