Association of Inflammatory Responses and ECM Disorganization with HMGB1 Upregulation and NLRP3 Inflammasome Activation in the Injured Rotator Cuff Tendon

Inflammation and extracellular matrix (ECM) disorganization following the rotator cuff tendon injuries (RCTI) delay the repair and healing process and the molecular mechanisms underlying RCTI pathology are largely unknown. Here, we examined the role of HMGB1 and NLRP3 inflammasome pathway in the inf...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Thankam, Finosh G., Roesch, Zachary K., Dilisio, Matthew F., Radwan, Mohamed M., Kovilam, Anuradha, Gross, R. Michael, Agrawal, Devendra K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995925/
https://ncbi.nlm.nih.gov/pubmed/29891998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27250-2
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