Association of Inflammatory Responses and ECM Disorganization with HMGB1 Upregulation and NLRP3 Inflammasome Activation in the Injured Rotator Cuff Tendon

Inflammation and extracellular matrix (ECM) disorganization following the rotator cuff tendon injuries (RCTI) delay the repair and healing process and the molecular mechanisms underlying RCTI pathology are largely unknown. Here, we examined the role of HMGB1 and NLRP3 inflammasome pathway in the inf...

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Publicado en:Sci Rep
Autores principales: Thankam, Finosh G., Roesch, Zachary K., Dilisio, Matthew F., Radwan, Mohamed M., Kovilam, Anuradha, Gross, R. Michael, Agrawal, Devendra K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995925/
https://ncbi.nlm.nih.gov/pubmed/29891998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27250-2
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