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Structural insights into the stimulation of S. pombe Dnmt2 catalytic efficiency by the tRNA nucleoside queuosine

Dnmt2 methylates cytosine at position 38 of tRNA(Asp) in a variety of eukaryotic organisms. A correlation between the presence of the hypermodified nucleoside queuosine (Q) at position 34 of tRNA(Asp) and the Dnmt2 dependent C38 methylation was recently found in vivo for S. pombe and D. discoideum....

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Rep
मुख्य लेखकों: Johannsson, Sven, Neumann, Piotr, Wulf, Alexander, Welp, Luisa M., Gerber, Hans-Dieter, Krull, Matthias, Diederichsen, Ulf, Urlaub, Henning, Ficner, Ralf
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995894/
https://ncbi.nlm.nih.gov/pubmed/29892076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27118-5
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