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Structural insights into the stimulation of S. pombe Dnmt2 catalytic efficiency by the tRNA nucleoside queuosine

Dnmt2 methylates cytosine at position 38 of tRNA(Asp) in a variety of eukaryotic organisms. A correlation between the presence of the hypermodified nucleoside queuosine (Q) at position 34 of tRNA(Asp) and the Dnmt2 dependent C38 methylation was recently found in vivo for S. pombe and D. discoideum....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Johannsson, Sven, Neumann, Piotr, Wulf, Alexander, Welp, Luisa M., Gerber, Hans-Dieter, Krull, Matthias, Diederichsen, Ulf, Urlaub, Henning, Ficner, Ralf
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995894/
https://ncbi.nlm.nih.gov/pubmed/29892076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27118-5
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