Structural insights into the stimulation of S. pombe Dnmt2 catalytic efficiency by the tRNA nucleoside queuosine

Dnmt2 methylates cytosine at position 38 of tRNA(Asp) in a variety of eukaryotic organisms. A correlation between the presence of the hypermodified nucleoside queuosine (Q) at position 34 of tRNA(Asp) and the Dnmt2 dependent C38 methylation was recently found in vivo for S. pombe and D. discoideum....

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Johannsson, Sven, Neumann, Piotr, Wulf, Alexander, Welp, Luisa M., Gerber, Hans-Dieter, Krull, Matthias, Diederichsen, Ulf, Urlaub, Henning, Ficner, Ralf
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995894/
https://ncbi.nlm.nih.gov/pubmed/29892076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27118-5
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky