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Identification of human vaccinees that possess antibodies targeting the egg-adapted hemagglutinin receptor binding site of an H1N1 influenza vaccine strain

Human influenza viruses passaged in eggs often acquire mutations in the hemagglutinin (HA) receptor binding site (RBS). To determine if egg-adapted H1N1 vaccines commonly elicit antibodies targeting the egg-adapted RBS of HA, we completed hemagglutinin-inhibition assays with A/California/7/2009 HA a...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Garretson, Tyler A., Petrie, Joshua G., Martin, Emily T., Monto, Arnold S., Hensley, Scott E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995672/
https://ncbi.nlm.nih.gov/pubmed/29861178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2018.05.086
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