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Hypoxia inducible factor-1 in clinical and experimental aortic aneurysm disease

OBJECTIVE: Mural angiogenesis and macrophage accumulation are two pathological hallmarks of abdominal aortic aneurysm (AAA) disease. The heterodimeric transcription factor, hypoxia inducible factor (HIF)-1, is an essential regulator of angiogenesis and macrophage fucntion. In this study we investiga...

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Detalhes bibliográficos
Publicado no:J Vasc Surg
Main Authors: Wang, Wei, Xu, Baohui, Xuan, Haojun, Ge, Yingbin, Wang, Yan, Wang, Lixin, Huang, Jianhua, Fu, Weiguo, Michie, Sara A, Dalman, Ronald L
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995616/
https://ncbi.nlm.nih.gov/pubmed/29242064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2017.09.030
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