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Structure-guided design and functional characterization of an artificial red light–regulated guanylate/adenylate cyclase for optogenetic applications

Genetically targeting biological systems to control cellular processes with light is the concept of optogenetics. Despite impressive developments in this field, underlying molecular mechanisms of signal transduction of the employed photoreceptor modules are frequently not sufficiently understood to...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Etzl, Stefan, Lindner, Robert, Nelson, Matthew D., Winkler, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995499/
https://ncbi.nlm.nih.gov/pubmed/29695503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003069
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